New project
ISO/AWI TS 13013
An optimized bronchoalveolar lavage fluid analysis method in inhalation toxicity studies of nanomaterials
Reference number
ISO/AWI TS 13013
Edition 1
© ISO 2025
New project
Under development
Drafting has started.

Abstract

This technical specification (TS) provides an optimized BALF analysis method in inhalation toxicity studies of nanomaterials. This technical specification will include the collection and preparation method for the BALF analysis in the aspect of inflammatory cell counts and levels of lactate dehydrogenase, total protein, and inflammatory mediators. In addition, this TS includes nanomaterial-specific considerations, such as inflammation patterns, proposed inflammatory mediators, and interferences in measurements. This TS is optimized for half-lung lavage of Sprague-Dawley (SD) rats but also provides information for the lavage volume of different strains and volume-determining parameters.

General information

  • Status
     : Under development
    Stage
    : New project approved [10.99]
  • Edition
     : 1
  • Technical Committee :
    ISO/TC 229
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Life cycle

Sustainable Development Goals

This standard contributes to the following Sustainable Development Goal

12
Responsible Consumption and Production

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